Sorry, Readability was unable to parse this page for content.
Friday, October 28, 2011
Thursday, October 27, 2011
Scientists have identified the genetic blueprint of the giant intestinal roundworm, Ascaris suum, revealing potential targets to control the devastating parasitic disease, ascariasis which affects more than one billion people in China, South East Asia, South America and parts of Africa, killing thousands of people annually and causing chronic effects in young children.
Dr Aaron Jex and Professor Robin Gasser from the University of Melbourne's Faculty of Veterinary Science led the international research project which was published in the journal Nature today [Oct. 27].
The work has provided new insights to treat the condition ascariasis, identified by the World Health Organization as a key, neglected disease in urgent need of extensive research and significantly improved control.
"Sequencing the genome of Ascaris suum is a major step towards controlling the infection it causes because the more we know about the genetics of the parasite and how it works, the better we can fight it with novel treatments," Dr Jex said.
"From the genome sequence we have identified five high priority drug targets that are likely to be relevant for many other parasitic worms. New treatments are urgently needed and genome-guided drug target discovery is ideal for identifying targets that selectively kill the parasite and not the host.
"We also identified key information on how the parasite hides from the immune system, which is essential for any future vaccine development."
The team sequenced the nuclear genome of Ascaris suum which is an easier worm to study in the laboratory and mainly only infects pigs, but is very closely related to Ascaris lumbricoides which causes ascariasis in humans. The worms range from 15-30cm in length and are spread via eggs in contaminated food.
Ascaris lumbricoides is one of the most common parasites of humans, affecting more than one billion people in developing countries, particularly children, causing impaired physical and cognitive development, and in severe cases death, due to lack of nutrient absorption and intestinal blockage.
Ascaris suum also causes major production losses in swine farming due to reduced growth, failure to thrive and mortality.
University of Melbourne: http://www.unimelb.edu.au
Thanks to University of Melbourne for this article.
This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.
This press release has been viewed 75 time(s).
3 cups of coffee a day keeps skin cancer away?
Drinking copious amounts of coffee may reduce the risk of the most common type of skin cancer, a new study finds. Women in the study who drank more than three cups of coffee a day were 20 percent less likely to develop basal cell carcinoma.
Friday, October 14, 2011
Posted by Leet on October 11th, 2011
As the demand for their already popular internet marketing services continues to grow, Brave River Solutions has decided to create Driven Internet Marketing in order to better serve their clients. The new division is comprised of four main practice areas: search marketing, which includes search engine optimization and pay-per-click advertising; social media marketing; content marketing; and web and mobile design, which is comprised of conversion rate optimization, design and development.
While Brave River has long featured these offerings, Driven will afford the opportunity to build on the company?s expertise and grow their internet marketing services. ?We realized that the best way to deliver the best possible service and attention to our customers would be to expand our services and provide a dedicated internet marketing team to help our clients achieve success in their online endeavors,? said Ernie Gaines, President.
Through this expansion, search engine marketing, content marketing and link building have been added to Brave River?s already popular SEO services, allowing for fully integrated campaigns that will maximize website traffic and exposure. Driven has also made it possible for the company to expand its social media marketing services to include online reputation management and training programs on the most effective way to manage corporate identity through social media. But perhaps the most exciting element of the expansion is that it facilitates the integration of every element of online marketing.
No longer are companies forced to choose one company for their web design, one for their mobile development, one for their copywriting and another for their search marketing. Driven?s clients can rest assured that every aspect of their internet marketing is completely complementary to all other components and is managed by a group that is constantly working together to align their objectives. Brave River Solutions is proud to introduce Driven Internet Marketing and all that it has to offer.
About Driven Internet Marketing:
Driven Internet Marketing delivers strategic internet marketing solutions to B2C and B2B organizations in a variety of industries that includes manufacturing, hospitality, healthcare and ecommerce. Through their four dedicated practice areas, Driven manages and promotes businesses online, attracting new audiences and cementing loyalty among existing customers. To learn more about Driven?s internet marketing services, please visit www.driveninternetmarketing.com or call us toll-free at 1-855-231-1511.
Article source: http://www.pbn.com/Brave-River-Solutions-Expands-its-Services-with-Driven-Internet-Marketing,61808Responses are currently closed, but you can trackback from your own site.
Thursday, October 13, 2011
WASHINGTON ? United against Barack Obama, Senate Republicans voted Tuesday night to kill the jobs package the president had spent weeks campaigning for across the country, a stinging loss at the hands of lawmakers opposed to stimulus-style spending and a tax increase on the very wealthy.
The $447 billion plan died on a 50-49 tally that garnered a majority of the 100-member Senate but fell well short of the 60 votes needed to keep the bill alive. The tally had been 51-48, but Senate Majority Leader Harry Reid, D-Nev., switched his vote to "nay" so that he could force a future revote.
The demise of Obama's jobs package was expected, despite his campaign-style efforts to swing the public behind it. The White House and leaders in Congress were already moving on to alternative ways to address the nation's painful 9.1 percent unemployment, including breaking the legislation into smaller, more digestible pieces and approving long-stalled trade bills.
"Tonight's vote is by no means the end of this fight," Obama said in a statement after the vote. "Because with so many Americans out of work and so many families struggling, we can't take `no' for an answer."
The White House appears most confident that it will be able to continue a 2-percentage-point Social Security payroll tax cut through 2012 and to extend emergency unemployment benefits to millions of people ? if only because, in the White House view, Republicans won't want to accept the political harm of letting those provisions expire.
White House officials are also hopeful of ultimately garnering votes for the approval of infrastructure spending and tax credits for businesses that hire unemployed veterans.
"Now it's time for both parties to work together and find common ground on removing government barriers to private-sector job growth," House Speaker John Boehner, R-Ohio, said after the vote.
Democrats Ben Nelson of Nebraska and Jon Tester of Montana ? both up for re-election next year in states where Obama figures to lose ? broke with their party on Tuesday night's vote. Every Republican present opposed the plan.
Earlier in the day, Obama capped his weekslong campaign for the measure in an appearance typical of the effort ? a tough-talking speech in a swing state crucial to his re-election. Like earlier appearances, it seemed aimed more at rallying his core political supporters heading into the election than changing minds on Capitol Hill.
"Any senator who votes no should have to look you in the eye and tell you what exactly they're opposed to," Obama said to a union audience in Pittsburgh. "I think they'll have a hard time explaining why they voted no on this bill ? other than the fact that I proposed it."
Democrats were not wholly united behind the measure. In addition to Nelson and Tester, Sens. Jim Webb, D-Va., Joe Manchin, D-W.Va., and Joe Lieberman, a Connecticut independent who aligns with Democrats, said they oppose the underlying measure despite voting to choke off the filibuster.
Obama's plan would combine Social Security payroll tax cuts for workers and businesses and other tax relief totaling about $270 billion with $175 billion in new spending on roads, school repairs and other infrastructure, as well as unemployment assistance and help to local governments to avoid layoffs of teachers, firefighters and police officers.
Obama said that the plan ? more than half the size of his 2009 economic stimulus measure ? would be an insurance policy against a double-dip recession and that continued economic intervention was essential given slower-than-hoped job growth.
"Right now, our economy needs a jolt," Obama said. "Right now."
Unlike the 2009 legislation, the current plan would be paid for with a 5.6 percent surcharge on income exceeding $1 million. That would be expected to raise about $450 billion over the coming decade.
"Democrats' sole proposal is to keep doing what hasn't worked ? along with a massive tax hike that we know won't create jobs," Senate Minority Leader Mitch McConnell, R-Ky., said Tuesday, saying there are 1.5 million fewer jobs than when Obama's 2009 economic package became law. "Why on earth would you support an approach that we already know won't work?" McConnell said.
The White House and Democratic leaders, however, were pleased that the great majority of Democrats voted for the plan. Support among Democrats was shored up by replacing Obama's tax increases ? particularly a proposal to limit the value of itemized deductions for families making more than $250,000 ? with the surcharge on annual income over $1 million.
That millionaires proposal would hit about 392,000 households, according to an analysis by the Tax Policy Center, a Washington think tank. In 2013, the first year the tax would take effect, those wealthy households would see their taxes increase by an average of $110,500, according to the analysis.
Just before the vote on Obama's jobs plan, the Senate passed legislation aimed at punishing China for keeping its currency undervalued against the dollar. Lower-valued currency helps Chinese exports at the expense, bill supporters say, of American jobs.
Next, both the House and Senate will turn Wednesday to approving trade agreements with Colombia, Panama and South Korea that could create tens of thousands of jobs, one of the few areas of agreement between Republicans and the administration on boosting the economy.
In coming weeks and months, Democrats promise further votes on jobs. But it remains to be seen how much of that effort will involve more campaign-stoked battles with Republicans and how much will include seeking common ground in hopes of passing legislation.
Leaders of the GOP-controlled House have signaled they support tax cuts for small businesses and changes to jobless insurance to allow states to use unemployment funds for on-the-job training. And they've indicated they'll be willing to accept an extension of cuts to the Social Security payroll tax. But stimulus-style spending is a nonstarter with the tea party-infused chamber.
Tuesday's vote played out as disaffected crowds continued to occupy Wall Street, a square in Washington and parts of other cities around the country in protest of income inequality and related issues.
Obama advisers said they were working with Senate Democratic leaders on how and when to break out separate aspects of the overall jobs bill for votes.
Even before Tuesday's defeat, the White House was casting the Senate vote as but the first act in what one Obama adviser called a long-term play ? essentially, an autumn full of action to force Congress to take action on jobs. Senior Obama officials said it was important for the Senate to act to keep pressure on the Republican-led House.
Sen. Tom Coburn, R-Okla., was recuperating from surgery and did not vote.
Associated Press writers Darlene Superville in Pittsburgh and Erica Werner in Washington contributed to this report.
- Wednesday, October 12, 2011, 5:33
- 47 views
Watch The Vampire Diaries s03e05 The Reckoning Online Streaming Video. Here yours preferred teen drama The Vampire Diaries back on the track, if you enjoy The Vampire Diaries so you?d also love to catch up The Vampire Diaries s03e05 which is set to publicize on October 13, 2011 on The CW Channel. The title generated to The Vampire Diaries s03e05 is ?The Reckoning?, wow sounds so exciting. I know all episode is exciting to catch up and because of that, you shouldn?t miss on this episode.
Complete synopsis and summary here you can read. Elena, Bonnie, Matt and Tyler decide to oblige Caroline when she urges them to celebrate Senior Prank Night, but uninvited guests make for a deadly evening. Damon convinces Jeremy that his connection to the other side may be the way to defeat Klaus. Klaus uses Stefan for more dangerous and brutal intentions.
Despite all that has happened, Caroline (Candice Accola) is determined to see that Elena (Nina Dobrev), Bonnie (Kat Graham), Matt (Zach Roerig) and Tyler (Michael Trevino) all enjoy a traditional Senior Prank Night before the school year begins at Mystic Falls High School. However, when uninvited guests show up, it doesn?t take long for the evening to take a deadly turn. Damon (Ian Somerhalder) convinces Jeremy (Steven R. McQueen) that he can use his new connection to the other side to help find a way to defeat Klaus (Joseph Morgan). Finally, Klaus deepens his hold on Stefan (Paul Wesley) and uses him for increasingly violent and dangerous purposes.
As a great TV show that is very creative, we believe The Reckoning will be an important episode. For that, do not forget to watch The Vampire Diaries s03e05 The Reckoning Online Streaming Video. It?s up to you, you can watch it streaming via the Internet, or through a television at home.
- Watch Parenthood Season 3 Episode 5 Nora Online Stream
- Watch Dexter Season 6 Episode 2 Online Free
- Watch Awkward s01e11 Episode 11 and 12 Fateful; I Am Jenna Hamilton Online Streaming Video
- Watch Dancing with the Stars Season 13 Episode 7 Online Free Streaming
- Watch The X Factor Season 8 Episode 13 Online Free
About the Author
chamakh has written 88 stories on this site.
Gravatars are small images that can show your personality. You can get your gravatar for free today!
You must be logged in to post a comment.
Wednesday, October 12, 2011
ScienceDaily (Oct. 12, 2011) ? An international team of researchers has discovered the vast majority of the so-called "dark matter" in the human genome, by means of a sweeping comparison of 29 mammalian genomes. The team, led by scientists from the Broad Institute, has pinpointed the parts of the human genome that control when and where genes are turned on. This map is a critical step in interpreting the thousands of genetic changes that have been linked to human disease.
Their findings appear online October 12 in the journal Nature.
Early comparison studies of the human and mouse genomes led to the surprising discovery that the regulatory information that controls genes dwarfs the information in the genes themselves. But, these studies were indirect: they could infer the existence of these regulatory sequences, but could find only a small fraction of them. These mysterious sequences have been referred to as the dark matter of the genome, analogous to the unseen matter and energy that make up most of the universe.
This new study enlisted a menagerie of mammals -- including rabbit, bat, elephant, and more -- to reveal these mysterious genomic elements.
Over the last five years, the Broad Institute, the Genome Institute at Washington University, and the Baylor College of Medicine Human Genome Sequencing Center have sequenced the genomes of 29 placental mammals. The research team compared all of these genomes, 20 of which are first reported in this paper, looking for regions that remained largely unchanged across species.
"With just a few species, we didn't have the power to pinpoint individual regions of regulatory control," said Manolis Kellis, last author of the study and associate professor of computer science at MIT. "This new map reveals almost 3 million previously undetectable elements in non-coding regions that have been carefully preserved across all mammals, and whose disruptions appear to be associated with human disease."
These findings could yield a deeper understanding of disease-focused studies, which look for genetic variants closely tied to disease.
"Most of the genetic variants associated with common diseases occur in non-protein coding regions of the genome. In these regions, it is often difficult to find the causal mutation," said first author Kerstin Lindblad-Toh, scientific director of vertebrate genome biology at the Broad and a professor in comparative genomics at Uppsala University, Sweden. "This catalog will make it easier to decipher the function of disease-related variation in the human genome."
This new map helps pinpoint those mutations that are likely responsible for disease, as they have been preserved across millions of years of evolution, but are commonly disrupted in individuals that suffer from a given disease. Knowing the causal mutations and their likely functions can then help uncover the underlying disease mechanisms and reveal potential drug targets.
The scientists were able to suggest possible functions for more than half of the 360 million DNA letters contained in the conserved elements, revealing the hidden meaning behind the As, Cs, Ts, and Gs. These revealed:
- Almost 4,000 previously undetected exons, or segments of DNA that code for protein
- 10,000 highly conserved elements that may be involved in how proteins are made
- More than 1,000 new families of RNA secondary structures with diverse roles in gene regulation
- 2.7 million predicted targets of transcription factors, proteins that control gene expression
"We can use this treasure trove of new elements to revisit disease association studies, focusing on those that disrupt conserved elements and trying to discern their likely functions," said Kellis. "Using a single genome, the language of DNA seems cryptic. When studied through the lens of evolution, words light up and gain meaning."
The researchers were also able to harness this collection of genomes to look back in time, across more than 100 million years of evolution, to uncover the fundamental changes that shaped mammalian adaptation to different environments and lifestyles. The researchers revealed specific proteins under rapid evolution, including some related to the immune system, taste perception, and cell division. They also uncovered hundreds of protein domains within genes that are evolving rapidly, some of which are related to bone remodeling and retinal functions.
"The comparison of mammalian genomes reveals the regulatory controls that are common across all mammals," said Eric Lander, director of the Broad Institute and the third corresponding author of the paper. "These evolutionary innovations were devised more than 100 million years ago and are still at work in the human population today."
In addition to finding the DNA controls that are common across all mammals, the comparison highlighted areas that have been changing rapidly only in the human and primate genomes. Researchers had previously uncovered two hundred of these regions, some of which are linked to brain and limb development. The expanded list -- which now includes more than 1,000 regions -- will give scientists new starting points for understanding human evolution.
The comparison of many complete genomes is beginning to offer a clear view of once indiscernible genomic regions, and with additional genomes, that resolution will only increase. "The power of this resource is that it continues to improve with the inclusion of more species," said Lindblad-Toh. "It's a very systematic and unbiased approach that will only become more powerful with the inclusion of additional genomes."
Other Broad researchers who contributed to this work include Manuel Garber, Or Zuk, Michael F. Lin, Pouya Kheradpour, Jason Ernst, Evan Mauceli, Lucas D. Ward, Michele Clamp, Sante Gnerre, Jessica Alf?ldi, Jean Chang, Federica Di Palma, Mitchell Guttman, David B. Jaffe, Irwin Jungreis, Marcia Lara, Jim Robinson, Xiaohui Xie, Michael C. Zody, and members of the Broad Institute Sequencing Platform and Whole Genome Assembly Team.
This project was supported by the National Human Genome Research Institute, National Institute for General Medicine, the European Science Foundation, National Science Foundation, the Sloan Foundation, an Erwin Schr?dinger Fellowship, the Gates Cambridge Trust, Novo Nordisk Foundation, University of Copenhagen, the David and Lucile Packard Foundation, the Danish Council for Independent Research Medical Sciences, and The Lundbeck Foundation.
Recommend this story on Facebook, Twitter,
and Google +1:
Other bookmarking and sharing tools:
The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by Broad Institute of MIT and Harvard, via EurekAlert!, a service of AAAS. The original article was written by Haley Bridger.
- Kerstin Lindblad-Toh, Manuel Garber, Or Zuk, Michael F. Lin, Brian J. Parker, Stefan Washietl, Pouya Kheradpour, Jason Ernst, Gregory Jordan, Evan Mauceli, Lucas D. Ward, Craig B. Lowe, Alisha K. Holloway, Michele Clamp, Sante Gnerre, Jessica Alf?ldi, Kathryn Beal, Jean Chang, Hiram Clawson, James Cuff, Federica Di Palma, Stephen Fitzgerald, Paul Flicek, Mitchell Guttman, Melissa J. Hubisz, David B. Jaffe, Irwin Jungreis, W. James Kent, Dennis Kostka, Marcia Lara, Andre L. Martins, Tim Massingham, Ida Moltke, Brian J. Raney, Matthew D. Rasmussen, Jim Robinson, Alexander Stark, Albert J. Vilella, Jiayu Wen, Xiaohui Xie, Michael C. Zody, Jen Baldwin, Toby Bloom, Chee Whye Chin, Dave Heiman, Robert Nicol, Chad Nusbaum, Sarah Young, Jane Wilkinson, Kim C. Worley, Christie L. Kovar, Donna M. Muzny, Richard A. Gibbs, Andrew Cree, Huyen H. Dihn, Gerald Fowler, Shalili Jhangiani, Vandita Joshi, Sandra Lee, Lora R. Lewis, Lynne V. Nazareth, Geoffrey Okwuonu, Jireh Santibanez, Wesley C. Warren, Elaine R. Mardis, George M. Weinstock, Richard K. Wilson, Kim Delehaunty, David Dooling, Catrina Fronik, Lucinda Fulton, Bob Fulton, Tina Graves, Patrick Minx, Erica Sodergren, Ewan Birney, Elliott H. Margulies, Javier Herrero, Eric D. Green, David Haussler, Adam Siepel, Nick Goldman, Katherine S. Pollard, Jakob S. Pedersen, Eric S. Lander, Manolis Kellis. A high-resolution map of human evolutionary constraint using 29 mammals. Nature, 2011; DOI: 10.1038/nature10530
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Internet Marketing Center Towards your Online Business Career Success
Everyone needs a mentor. If you want to be successful in your chosen college degree, you need to be under the care of your college professors who have the necessary knowledge and expertise in your chosen college degree. Even starting Internet marketers needs to be educated by Internet marketing experts. Once you have plunged in Internet marketing without learning first the necessary knowledge and strategies, expect that it will be the cause of the downfall of your Internet marketing career. Thus, to avoid losing what you already have, you need somebody to guide you throughout your Internet marketing career.
And that is why Internet Marketing Center is built.
Internet Marketing Center was founded in 1996 by the late Internet marketing expert Corey Rudl that is focused on the research, development, and test of cost efficient e business and e commerce marketing strategies and automated solutions that could be applied to small and home based business owners and produce revenues and profits. As one of the recognized leader in the Internet marketing industry, Internet marketing Center continues to develop practical and cost efficient marketing software and strategies for online based businesses of all size. It is exclusive of millions of dollars worth of income generated by thousands of Internet marketing business worldwide.
How can Internet Marketing Center help you with your Internet marketing career?
1.Choosing a Product you will be provided with a wide selection of products or services that you can endorse over the Internet. You will learn how to start with your Internet marketing website, such as its design and development, web page optimization, registering under a unique and original domain name, and others.
2.Writing Sales Copy sales copy is essential to Internet marketing, since it will serve as your ?campaign material in endorsing your products or services.
3.Getting Internet Traffic you will not succeed on your Internet marketing career if you do not have Internet traffic to convert into loyal product evangelists. You will learn much about the promotional tools that are used and proven effective in marketing your site and its products or services.
4.Search Engines this will bring you the targeted Internet traffic that you want towards your website. You will learn several search engine factors that have direct effects on your website, such as keywords, optimized web pages, search engine spider, unique niches, and others.
5.Starting a Newsletter by getting subscribers to read newsletters, you will be able to build a strong clientele base.
6.Testing Email Marketing Solutions emails are now widely used by Internet marketers in advertising their products and getting the clients that they need. There are thousands of Internet marketers out there and getting them as affiliates will surely boost your Internet marketing business. You will learn how to recruit affiliates once you have established your Internet marketing company.
There are hundreds to thousands of success stories about online marketers who sought the help of Internet Marketing Center. Try Internet Marketing Center and see the difference!
Posts Related To :
Internet Marketing Seo
SEO Facts and Basics-Small Leap yet Giant Step Towards Internet Marketing Success Hearing the acronym SEO is not new for most Internet marketers. Before discussing SEO to Internet marketing...
Internet Marketing Promotion
No Money for your Internet Marketing Business Promotion? Use Free and Low-Cost Marketing Alternatives Starting an Internet marketing business is probably the best way of growing a residual income...
Best Internet Marketing Strategies
Which is better, a traditional pet shop or an online pet shop? By comparing these two specific examples, you will be able to figure out why Internet marketing is very popular among entrepreneurs and...
Internet Marketing At A Glance
There now exists two facades of Internet users those who are in pursuit of the latest and fresh information about anything of interest and those who are seeing the Internet as an opportunity to earn...
Internet Marketing Affiliate Program
Earn 5-Figure Income every Month through Internet Affiliate Marketing Program The name of their game is Internet affiliate marketing program, and they are making tens to hundreds of dollars per...
Tags: Business, Career, Center, Internet Marketing, Marketers, Online, products, Strategies, Success 0 Comments 19 views
Search Article Related To: Internet Marketing Center Towards your Online Business Career Success Or find Article with this Tag: Business, Career, Center, Internet Marketing, Marketers, Online, products, Strategies, Success
Tuesday, October 11, 2011
Seniors and Wandering & Alzheimer?s
Wandering can be a frightening experience for the family of a senior with Alzheimers.? It is important to find out as much as you can as to why and where they wander.? This article is a good start towards understanding and learning from senior care professionals about wandering.
Ask the home care agency for details of their staffinf an agency without RN?s or Case Managers will not be your best bet so ask the right questions.
Lisa Marie Blaskie RN, CCM, CSA
Wandering is one of the greatest challenges faced by family caregivers where a senior?has Alzheimer?s or other memory loss. Over 60% of Alzheimer?s patients will become lost at some time. Most are gone only briefly, though long enough to frighten their elder loved ones. Others may be lost for an extended period of time, and unfortunately, there are news reports each year of missing Alzheimer?s patients who are never located. It is a sobering fact that if a person with dementia is lost for over 24 hours, he or she is likely to suffer a fall or other serious injury, or even death from injury or exposure. Reports one family caregiver, ?The thought that Dad would climb onto a bus at the corner and we would never find him again keeps me awake at night, even on nights when he is getting a good night?s sleep.?
Why do elders with dementia wander?
For Elders with Alzheimer?s or other memory loss, confusion and disorientation make it increasingly difficult to recognize familiar faces and places, even a spouse or child, or a lifetime home. Geriatricians point out that the term ?wandering? is something of a misnomer, because many times, in the person?s mind, his or her activity is not purposeless. She may be looking for the bathroom but be unable to find it. He may think it is time to leave for work, even if he retired years before. A great-grandmother might be searching for her children, in the belief that they are still small and in need of her care.
Other factors that contribute to wandering include restlessness, agitation and stress; boredom and lack of a sense of purpose; sleep disorders; physical pain; and the side effects of medications.
Keeping your senioe safe
When a senior with dementia wanders, family often decide that a nursing home or memory care community is the best choice for the person. However, many patients fare much better at home, in familiar surroundings. How can families keep their loved one safe at home, for as long as possible? Talk to Home care agencies that have RN?s or Case Mangers on staff who are specically trained to offer these suggestions:
Observe your senior?loved one?s patterns. The first step is to understand as best you can the reason for your senior?s wandering. What are his ?triggers?? Where does he usually try to go? During what time of day is he most restless? Does he seem to be looking for something, someone, or someplace?
Adapt the home to keep your loved one safe. Beyond the usual ?aging in place? home modifications, you can add special locks to doors, safety gates to prevent exit, and an alarm that will sound if the front door is open. Talk to a Agency Case Manager?for information about other home modifications.
Hire professionals for?in-home care. With jobs and other obligations, families are often overwhelmed Agency home caregivers are trained to provide a watchful but non-intrusive presence in the home. Says one home care aide, ?We?ve learned that for many seniors, ?hovering? makes things worse and leads to increased wandering.? Families report that they have a more peaceful relationship with their loved one when the? home care?agency caregiver takes over some of the basic personal care tasks.
Written By : Jacob Munoz
ComForcare Home Care?helps many families with their eldercare caregiving needs as well as personal injuries, workers compensation, cosmetic surgery rehab and new mom care.
??If you have questions or need help with home care for your loved one, call us!??We are a home care agency providing in home care in San Francisco, CA and the surrounding area.? Please call ? 415.420.6114 or 800.993.2945 to Lisa Marie Blaskie RN, CCM, CSATags: familiar faces, period of time, exposure reports, family caregiver, Caregivers San Francisco, lisa marie
Monday, October 10, 2011
LOS ANGELES ? Organizers say a two-day auction of more than 700 costumes, scripts, awards and memorabilia from the estate of film star John Wayne brought in $5.4 million.
Heritage Auctions said Friday that the auction included items such as Wayne's last driver's license, a holster and gun belt from the film "El Dorado" and an eye patch from the 1969 movie, "True Grit."
The green wool beret Wayne wore in "The Green Berets," went for $179,250 and a cowboy hat worn in "Big Jake" and "The Cowboys" fetched $119,500.
The items had been kept by Wayne's family since his 1979 death from cancer.
A portion of the proceeds will be used by the John Wayne Cancer Foundation to help fund cancer research, treatment and education.
Question by Mee: dating issues in lebanon?
in leb society?especially palestinian christian families or arab families in general, what does it mean by the following when it comes to relationships.
im christian european..from the uk and my relationship was stopped with a palestinian guy due to me being older than him. it was nothing to do with sex or a visa it was a totally genuine relationship for over 2yrs, but his family made him choose and said i wasnt suitable. i was unhealthy for him cos of my age. i dont understand some of the other things relating to his family issues that were said and wondered if anyone could enlighten me as to what these mean.
1. when it comes to the family making you choose between your b/f or g/f and them, does the family always come first or do you know of men that have walked away from their families and been strong and gone to the one that they love despite what the family has thought.
2. this ultimatum of its either her or us?what happens to the guy. do the family stop speaking to him altogether and disown him or do they make him feel guilt for the rest of his life but still talk to him. what happens if he moves away with you to europe and starts a new life, do arab families forgive in general or does it depend on each family.
3. what is meant by relatives will interfere and examine the relationship and not let us be. we would be defending the relationship rather than living it and having to convince the family.
4. i have spoken to many leb christians and arabs on this matter in the past few months and have been told that leb society is open minded to issues like this, such as age gap relationships where the woman is older. yet, my ex told me that the society there would be cruel to us and wouldnt accept our relationship cos it was different. i have also looked on the internet and found that a few famous leb stars who are older women in their 40s have had relationships with younger men and it has been scorned on by the media there and public cos it is not normal. so what is the situation with things like this..did he lie to me or was he telling the truth. what do you think of this issue ie the woman being older and do you know of any relationships in leb like this or know if times are changing there to start accepting that woman can be older in a relationship these days as well as the man.
love has no age limits..its about two people being together and committing to each other. lots of times these relationships are actually stronger cos they are different and you fight for them more and know that what you have is special and different to other peoples.
we talk on skype still every few weeks. he cries and has told me so many times if any happens to me something will happen to him. i can see he is heartbroken. he said he doesnt want another relationship and will stay alone for the rest of his life. i know that it was his mother more than anything that did this. all along he told me from the beginning how close they were and during the months he fought it was her approval he wanted the most. when he told her we were marrying she had a panic attack and chest pains threw him out of the house.
he panicked when that happened and the next day that was when it was over between us. he has told me since that her happiness comes before his and no matter what he cant lose her. so i know that his mother was the main reason for us breaking up. i dont understand how you can make a son choose when he is so happy. he pleaded with her and told her he couldnt live without me, but i also know what if he wanted me so much he would have left. in my heart i know he was a coward and not strong enough and he walked away and left me, but im devastated cos ive lost the best person i ever knew. i know i wont find a love like this again, what i felt for him will be hard to replicate with someone else. at my age also, i feel that this might have been my last chance at happiness and maybe now i should also give up too on love and accept being on my own. im 43 he was 26.
in response to angie..
yes we did meet..we had a couple of holidays each lasting two weeks and we were inseparable. he doesnt want children at all..and i mean he is seriously not having any. even if i was younger and i got pregnant he would have gone crazy cos he doesnt want to be a father. he is totally against the idea cos of illness in his family chain. it wasnt online only. it was real too. we were planning a future and a life here in the uk with me. we were very happy but choosing between me and his parents made him scared. he said he has torn himself apart over this until he reached the conclusion that it was either me or the people who raised him. i can still have kids..i havent had any yet and im fit and healthy. women here in the uk have kids till 48 easily. his own mother had him at 37. shes the same age as my mother..ie in her 60?s. so is his father, as its second marriage.
Answer by Tyler
Families can exert allot of pressure on a relationship. Sometimes the families win, sometimes they don?t. Look at Prince Charles and Camilla. He married her in spite of the world and they are still together. I once was going to marry a Greek man but his mom vehemently disapproved and 2 yrs later she won out. She bribed him with a nice stereo? and of an arrangement with a dowried woman with car and house. Your age gap is insignificant in modern day society but to closed minded society it is something they will focus on maybe for your life time. I don?t want you to be discouraged but if this man does it for you, then marry and move to the UK. If you move you may never get their approval but you won?t feel the brut of their disapproval on a daily basis. In time they may turn him against you.
I?ve been married to a younger man for 32 yrs. I had children with him and lived all over the world with them. We settled close to his family but I don?t have a close relationship with them. Different religious ideas. I have a life independent of his family and they don?t like it. I tell him numerous times to hang out with them and he does every now and then. But he is most himself around me. We go to family functions, I am cordial but I do keep my distance. Focus on your career, money is power. Don?t give them an edge by offerings of financial gifts.
Add your own answer in the comments!
- Q&A: dating issues i need help PLEASE?
- Dating older man? consider these issues
- Q&A: What do you think are the biggest problems with teen dating abuse? What issues do you think need to be ad?
- Q&A: Being a single Dad with three girls. Dating issues.?
- Q&A: Family problems with dating a woman that is 18 years older than me?
Sunday, October 9, 2011
A Luxurious Bed and Breakfast Chateau for Guests to Normandy, France in Europe
Report URL:http://www.articlesbase.com/lodges-content articles/a-luxurious-bed-and-breakfast-chateau-for-visitors-to-normandy-france-in-europe-5057546.html
Hello. ?I?m a web site developer, writer, musician, genuine estate investor, normal well being fanatic, minimalist, and the creator of 2 ebooks, Make Huge Earnings Flipping Florida Land and The Shift Diet program.
People traveling to Europe, traveling to France in particular, have a great deal of alternatives to make. They can keep at a brand name title resort in a major city like Paris. They can remain at a little luxurious resort in the French countryside of Normandy. They can stay at a French bed and breakfast at a little city or village someplace inbetween. Or, they can do a combination of these.
For a French Bed and Breakfast Unlike other Tiny Luxurious Accommodations, Book a Reservation at Chateau D? L? Isle Marie.
For travelers to France seeking for a exclusive bed and breakfast, that brings together a chateau experience with staying in a castle, that can serve as a romantic getaway or an ideal retreat for each enterprise or pleasure, the chateau d? L? Isle-Marie, an stylish chateau bed and breakfast in Normandy, France, just a brief drive from an place of signficant locations like Mont St. Michel and the D-Day landing beaches.
Isle Marie is a luxury boutique B&B chateau Inn close to Bayeux, Mont St. Michel and the D-Day landing shorelines.
Not like other modest luxury accommodations in the area of Normandy, France adn Bayeux, France, the chateau Isle Marie offers company a alternative of two different chateaus in which to remain. In the principal chateau, company are offered rooms with luxurious and antique furnishings, and possibilities to get pleasure from the drawing space on the first floor, as nicely as participate in the complimentary breakfasts involved for guests. In the visitor chateau, guests rent their individual self catering apartment, which incorporates a cooking area, making it possible for them to store for foods and dwell like a regional although visiting France.
Guests can choose in between luxurious bed and breakfast lodging accommodations in the chateau, or self-catering apartments in the nation manor residence. Normandy is the perfect escape for a household getaway and Isle Marie can be rented exclusively for this kind of a family get-jointly. Within hours from zipping across the channel, or a a few-hour drive from Paris, you can enjoy the cozy boutique feel of the intimate little resort.
Normandy is heralded as the cradle of the Dukes of Normandy. Our castle also, has 1000 decades of historical past with the same household living here since the 11th century.
So if you are browsing for a property absent from residence, a chateau week-stop break from Paris, a romantic getaway, or a historical past immersion expertise why not pick one particular four star Hotel de Charme in Normandy?
Normandy is a great vacation spot for a golfing vacation. Its prosperous and varied landscape gives a memorable backdrop for the many golf courses in the vicinity.
Travel and Leisure journal based mostly in New York chose our private chateau as 1 of best fifty romantic getaways around the world. Just lately Departures, the daily life-fashion journal for American Convey luxurious journey showcased Isle-Marie in a 4 page post with the title: ?Shhh?. The Secret Chateau.?
Isle-Marie can arrange transportation from Paris to our chateau, as properly as D-Day tours of the landings with our non-public historical information.
The destinations guests to this Normandy, France bed and breakfast, can count on to see are distinct from other European travel spots due to the fact of their historical signficance. They contain the adhering to.
On a modest rocky island that is surrounded by the waters of the English Channel, about one km from the north coast of France at Normandy, sits the Mont St Michel, a medevial Benedictine Abbey and church. Legend has it that the abbey was built soon after the Archangel Michael appeart to Aubert, Bishop of Avranches, instructing him to develop a church on the rocky islet. When Aubert overlooked his recommendations, the tale goes, Michael burned a hole in his skull, as a result inspiring him to start the building of the edifice.
During the time of the French Revolution, the abbey on Mont St. Michel was converted to a jail. Then later on, influential figures like Victor Hugo and other people campaigned to restore the Mont St. Michel as a countrywide treasure. In 1874, the Mont St Michel was declared an historic monument. Currently, it is open for guests and sees hundreds of 1000?s of guests a yr to witness this prosperous architectural treasure.
Aptly named ?Bloody Omaha?, Omaha Beach, in Normandy, was covered in anti-tank and anti-landing craft road blocks. The allied air bombardment had been largely ineffective and, as background has demonstrated, little went to program. The American Memorial at St. Laurent and the Omaha Beach Museum bear witness to this. This is the only battlefield in heritage exactly where troops had to run in the direction of enemy fire to reach cover. The visitor middle is designed to complement and broaden the experiene of browsing the American cemetary in Normandy by having to pay tribute to the values embodied by the sacrifice of American and Allied soldiers.
At first, a code name for the Normandy seashores for the duration of the D-Day invasion, Utah Seaside stands as a monument to the American and Allied forces productive try to establish a landing zone, in order to move in the military in their subsequent push towards Cherbourg. Presently, Utah Seaside is property to a museum and well-known for historical excursions in the region, that supply an up shut watch of what it was like for the American and Allied soldiers who so courageously fought for flexibility.
Barfleur, a fishing village with modest homes and a abundant history, is one particular of them most charming villages in France. This city is really worth going to for travelers to Europe and France who enjoy discovering, photography, and understanding about heritage.
Barfleur was the Anglo-Norman Kingdom?s foremost port in the center ages. A significant medallion fixed to a rock in the harbor marks the embargination level of William the Conquerors fleet before the battle of Hastings in 1066.
In medevial moments shipwrecks ended up widespread. In 1120, the white ship sank off Barfleur. Prince William, sole reputable son of King Henry I, drowned, precipitating a succession crisis. In 1169, King Henry II had embargued at Barfleur after an inspection of his Norman fortresses and narrowly escaped drowning soon after his ship sunk throughout a storm. In his entourage was Henry D? Aigneaux, an ancestor, referred to as ?the most noble of the Barons of England?. Right now, the lighthouse of Gatteville, the 3rd biggest in the globe, gives ease and comfort to sea mariners as does the oldest lifeboat station in France.
Barfleur is a quaint fishing port dominated by the church of Saint nicholas and is lined with grey granite houses with terra-cotta tiled roofs, sophisticated chimneys and underscored by attic ?eyelid? windows.
You can go to the medevial courthouse of Saint Catherine, the house of Saint Marie Madeline Postel, and the Augustine Gardens.
Selected as 1 of the prettiest villages in France, Barfleur is frozen in time and encapsulates much of what individuals adore about Normandy. It undoubtedly inspired artist Paul Signac who formulated the neo-impressionist pointilist type.
Barfleur is a quick drive from the chateau Isle Marie.
Cartaret seaside is considered as one of the greatest seashores in Normandy. Positioned on the Western Coast of the Cotentin peninsula, south of Cherbourg, Carteret is a charming resort and fishing port and marina with some 300 moorings. The Carteret Cape is the very last of the big cpes of the Corentin, reverse the channel islands of Jersey. On a obvious day, the cliffs turn out to be a true balcony to see the Anglo-Norman Islands.
The West Coast of the Cotentin peninsula has a salty, Atlantic coast really feel to it with sand dunes dotted with wild flowers and a prolonged ribbon of distinct sandy beaches empty but for a handful of sand-yacht lovers. A line of green hills hosts church steeples, medevial churches, wind mills and the Rue der Ormes in which schooner captains had created their opulent residences?perfect for a day trip and bucket-and-spade seaside holiday.
Saint Saveur, birthplace of Barbey d? Aurevilly, is on the way to Cartenet and boasts a castle which dates from the 11th and 12th centuries when a feudal motte of the Norman barons was created here.
The Saint Saveur Chateau and the Isle-Marie Castle were the two important strategic medevial chateaux in Normandy that offered a fortress protection in opposition to the English in the course of the one hundred Years War.
The historic fortress with massivve 14th century towers and an imposing preserve even now stands. The metropolis walls were breached by cannon in the course of a siege and is thought to be between the initial sucessful employs of guns against metropolis partitions in historical past.
St Sauveur would have been the last battle scene shown in Spielberg?s ?Saving Private Ryan?, based mostly on the Niland brothers, if it had been centered on simple fact and not fiction.
Metropolis of painters and the cradle of impressionism. The sea stroll bordered with superbly preserved manifeste gardens helps make a nice walk along the mouth of the Seine. The wooden bell tower of the chcurch of Saint Catherine is the biggest church made out of wood in France. Hourfleur is one particular of the most picturesque ports in France and surely an selection for lunch on your way to the chateau.
Even though guests to Europe, exclusively Normandy, France and Bayeux, France have a range of lodges, motels, chateaus, castles, bed and breakfasts, self catering apartments, and even gites from which to choose to keep in for the duration of their trip holiday, this writer finds that a single of the greatest chateaus accessible is the Chateau Isle Marie, honored by initial travel magazine ?Travel & Leisure? as currently being a single of the top rated 50 romantic holiday destinations worldwide.
Although the Chateau D? L? Isle-Marie has gathered these honors like this from far and vast, it is reasonably priced, and gives a romantic hideaway and charming bed and breakfast remain for all kindsof travelers, singles, partners, people, regardless of whether they chose to stay in the guest
Tags: Augustine, Breakfast, Breakfasts, Chateau, Europe, France, Guests, Luxurious, Normandy, SaintTags: France, Breakfasts, Europe, Luxurious, Augustine, Chateau
Saturday, October 8, 2011
MILAN (Reuters) ? Moody's lowered its credit ratings on Italy's two biggest banks, Intesa Sanpaolo (ISP.MI) and UniCredit (CRDI.MI), on Wednesday following its recent downgrade of Italian sovereign debt.
On Tuesday, Moody's lowered its rating on Italy's bonds by three notches to A2, saying it saw a "material increase" in funding risks for euro zone countries with high levels of debt and warning that further downgrades were possible.
Italian banks have come under pressure in recent weeks because of the spreading debt crisis and are seen as vulnerable because of their vast holdings in Italian government bonds.
Rising government bond yields have also driven funding costs higher for domestic lenders.
Moody's said in a note it had cut UniCredit's long-term debt and deposit ratings to A2 from Aa3, concluding the review for possible downgrade initiated in May this year.
"Growth prospects for many of the group's key markets, and in particular Italy, have been cut in recent months, which is likely to make significant further improvement in profitability and asset quality more uncertain and difficult to achieve," Moody's said.
But the rating agency also pointed up the bank's improved capital adequacy and its robust liquidity, which has allowed it to cope with difficult market funding conditions.
The long-term debt of Intesa, Italy's biggest retail bank, was cut to A2 from Aa3. In a note Moody's noted Intesa's direct exposure to the Italian sovereign and its pronounced focus on domestic business.
The management of both UniCredit and Intesa Sanpaolo have said they currently have no funding problems.
Besides its downgrade of Italian banks, Moody's also cut its ratings on the debt of a series of state-controlled Italian companies including oil and gas group Eni (ENI.MI), utility Enel (ENEI.MI), defense company Finmeccanica (SIFI.MI) and power grid operator Terna (TRN.MI).
(Reporting By Stephen Jewkes; Editing by Bob Burgdorfer)
Friday, October 7, 2011
October 5, 2011
By Barbra Murray, Contributing Editor
CBRE Group Inc., formerly CB Richard Ellis Group Inc., has taken a big step toward the completion of its $940 million acquisition of substantially all of ING Group N.V.?s securities and management businesses. The commercial real estate firm ? already the largest in the world in terms of 2010 revenue ? just closed the purchase of ING Group?s real estate investment management operations in Asia, or ING REIM Asia. The procurement of ING REIM Asia marks the second stage of the nearly $1 billion transaction. Two down, one to go.
CBRE Group is in the process of incorporating ING REIM Asia into its existing Global Investment Management division in the region, which functions through company subsidiary CBRE Investors. The new entity?s operations span such leading global metropolitan destinations as Hong Kong, Shanghai, Seoul, Singapore, Taipei and Tokyo.
?This acquisition is a milestone that significantly enhances our talent, resources and market insight in Asia,? Matt Khourie, global president with CBRE Group and head of the firm?s Global Investment Management business, said. ?We now have the ability to offer investors an expanded array of investment programs across the risk-return spectrum in the dynamic markets throughout the region.?
During the first six months of 2011, CBRE Group?s revenue from its Global Investment Management business, which consists of operations in the U.S., Europe and Asia, totaled nearly $107.9 million, marking a substantial increase from the $86.3 million in revenue during the first six months of 2010.
ING Group?s European real estate investment management operations, ING REIM Europe, will be brought into the fold before the end of the year; CBRE Group anticipates a closing during the third quarter. When all is said and done, the firm will have relied on $400 million of new term loans and cash on hand to finance the REIM Asia and REIM Europe purchases. CBRE Group had raised $800 million of bank debt for the three-phase ING transaction, and spent the other $400 million to finance the first phase of the three-part deal, the acquisition of ING Clarion Real Estate Securities, which closed at the end of the second quarter.
Thursday, October 6, 2011
New evidence supports the theory that comets delivered a significant portion of Earth's oceans, which scientists believe formed about 8 million years after the planet itself.
The findings, which involve a University of Michigan astronomer, are published Oct. 5 online in Nature.
"Life would not exist on Earth without liquid water, and so the questions of how and when the oceans got here is a fundamental one," said U-M astronomy professor Ted Bergin, "It's a big puzzle and these new findings are an important piece."
Bergin is a co-investigator on HiFi, the Heterodyne Instrument for the Infrared on the Hershel Space Observatory. With measurements from HiFi, the researchers found that the ice on a comet called Hartley 2 has the same chemical composition as our oceans. Both have similar D/H ratios. The D/H ratio is the proportion of deuterium, or heavy hydrogen, in the water. A deuterium atom is a hydrogen with an extra neutron in its nucleus.
This was the first time ocean-like water was detected in a comet.
"We were all surprised," Bergin said.
Six other comets HiFi measured in recent years had a much different D/H ratio than our oceans, meaning similar comets could not have been responsible for more than 10 percent of Earth's water.
The astronomers hypothesize that Hartley 2 was born in a different part of the solar system than the other six. Hartley most likely formed in the Kuiper belt, which starts near Pluto at about 30 times farther from the sun than the Earth is. The other six hail from the Oort Cloud more than 5,000 times farther out.
The source of earth's oceans has been a subject for debate among astronomers for decades. Until now, asteroids were thought to have provided most of the water. Now, however, Herschel has shown that at least one comet does have ocean-like water.
"The results show that the amount of material out there that could have contributed to Earth's oceans is perhaps larger than we thought," Bergin said.
University of Michigan: http://www.umich.edu/
Thanks to University of Michigan for this article.
This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.
This press release has been viewed 58 time(s).
Wednesday, October 5, 2011
We didn't know it was possible to become legitimately choked up while watching Dancing With the Stars, but J.R. Martinez proved it possible Monday night.
There weren't many dry eyes left in the room following the Iraq War veteran's moving life story of injury and redemption, followed by an emotional dance.
After J.R. finished his rumba with Karina Smirnoff, the All My Children actor seemed taken aback by what he's been through - not just on DWTS but in life.
Here's Martinez's full segment on last night's show:
Only Ricki Lake (27) topped J.R. (26) among Monday's Dancing With the Stars scores. Along with Chynna Phillips (26), they look like the three to beat.